Apr 132024
 

Yesterday, Robert Reich’s column was about the Manhattan criminal charges against Donald Trump**. He explains in detail exactly why it is wrong to call it a “hush money” case. I umderstand, and I’m sure he also does, the temptation to find a way to distinguish it from all his other legal woes, so that people know instantly which case one is talking about. But it also plays into his hands. “New York election interference case” or “Manhattan election interference case” are two ways we can call a spade a spade and still make it clear what case is being alluded to.

This is a “Colorado leads the Way” story. I’m sad that it took this long. But I’m bursting with pride that it’s being done now.

Not to suggest there is such a thing as a good Republican today – but, you know, the House could have done a lot worse than Mike Johnson.

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Apr 122024
 

Yesterday, I heard from Trinette that she has a cold, and might not make it Sunday. I said let’s skip a week – I want you to be well. (Thoughts and prayers welcome.) Also, yes, I’m aware that O.J.Simpson died Wednesday. It’s not something I really want to discuss. But the New Yorker, the Atlanta Black Star, and The Root, are packed with discussion, so if anyone wants to, the resources exist.

I realize that conservative groups consistently mis-name themselves to suggest the opposite of whatever bug is in their brains when they form the group – but this is extreme even for them.

This is something Joe can do without Congress. and I think – but am not sure – that the Food for Thought might be another thing. If so, I’m all for it.

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Apr 112024
 

Yesterday, I finally took a few duck eggs out of the freezer ((I’m allergic to chicken eggs, n=but not to duck eggs or goose eggs) to use as toppers to corned beef hash (yes, I’m old – that used to be a popular meal, particularly for breakfast). I froze some when my source retired. Freezing eggs is an awkward business – you have to take them out of the shell, because if you don’t, they will break in the freezer, and you also have to at least pierce the yolk. And if you don’t want to use them all together, you need to put each one into a separate plastic bag. So hardboiled eggs are not an option. Traditionally, with hash, they were poached, but that’s not an option either, since the yolk is pierced. I just made a “valley” in the “mountain” of hash and put an egg (out of the plastic bag) into it, then microwaved it. It wasn’t as good as the meals I remember, but it wasn’t bad either. However, the best use of frozen (and then thawed) eggs is in baking. Maybe I’ll feel up to that eventually.

I always enjoy reading Amanda Marcotte. She sees things that otber people, including me, don’t. I don’t claim she’s always right, but what she has to say always bears consideration. I should point out that Salon, where she is a senior writer, is also now on substack (as is I presume her personal newsletter which they mention.)

As Nameless often says, good news is always welcome. And I find this news particularly good coming from Texas. I suppose the whiny Texas GOP will be taking it to the Supremes, but at least there are injunctions for the interim. And the Supremes might turn it down. If they’re smart enough (I know some are.)

Hanky Alert

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Apr 102024
 

Yesterday, Democratic Underground had this short eclipse video from Xitter. I’m not going to send you to Xitter, but the embed is worth watching. (If you read the comments, you’ll know it was first posted by Eric Swalwell.)

Because this is not exactly current events, I held it for a few days. Heather Cox Richardson reviews the history of Yellowstone and of the Antiquities Act. It made me realize how close we came to not having something I have always taken for granted – our National Park system. I’ll try not to take it for granted any more.

Well, this doesn’t look good for my Congressinal District (Not that anything ever looks good for my Congressinal District.) On the other hand,perhaps, with enough publicity about this creep (of course I mean Williams, not Fish)a Dem might be able to win – or at the very least to make a good showing, which might be able to carry forward to 2026.)

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Apr 092024
 

Yesterday, a member of Democratic Underground posted a new Biden-Harris campaign ad there. Wow. I’m going to provide the DU link (embedded YouTube videos don’t have the advertising) but also the regular YouTube link in case you need full screen, CC, and 75% speed, which I did, to fully appreciate it (or you can navigate to YouTube from the embed.) Hanky alert.

After addressing the Key Bridge tragedy and the tragedy for our nation that is Trump**, Robert Hubbell turned this weekend to immigration. If you want to skip the first part, it’s fairly east – it has its own headline, large and bold – “How foreign immigrants support the US economy.” In addition to his own words, he links to an interactive map where you can, if you wish, find ypour own county, possibly even city, and see how may live there, how much they pay in taxes, what their spendinh power is, and how many are eligible voters (naturalized and 18 or over. Just under half of my county’s are in this category.) And some other data as well. You probably already knew that immigrants are good for the country, but this will really open your eyes to just how much and in what ways that is so.

RFK Jr is best known for being Anti-Vax (Off Topic – but another article at the Daily Beast reveals that Anti-Vaxxers are now trying to take over a hospital.) But it appears he is not averse to accepting support from other shady types.

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Apr 082024
 

Yesterday, Trinette came by. I didn’t have a lot for her to do this week. I was working on my closet more than clutter. She says hi to all.

The Reich on the left is right as usual – about the likely event – and I hope he is equally right about the lag time. Much more than that and it will be too late. I apologize for not making a note of where i read this, but apparently some polling in swing states specifically showed voters positivw abot their state’s economy but negative about the national economy (which makes little sense -but i guess that’s why they’re swing states.)

I don’t know how public this knowledge is – by which I mean, technically it’s public knowledge, but no one will know it if news outlets don’t pick it up.

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Apr 072024
 

Yesterday, The radio opera was Donizetti’s “L’Elisir d’Amore” (“The love Potion”) and I’m afraid I slept through half of it. My alarm went off and I decided not to get up. I’m not a big Pavarotti fan, and while there were other major stars of the time, including one with whom I shared a violin teacher (not of course at the same time – decades apart actually) I just wasn’t inspired to get up then. I did get up in time fpre the second act (there are only two). One of the four main characters is a “snake oil salesman” and i see enough of that in real life.

Heather Cox Richardson is an historian, not an economist – but you don’t really need to be an economist to know that “supply-side” economics does not work. You just need to be over 40 and not blind. The Biden/Sanders video she speaks of is the second with Biden’s name on it in the list of Xitter videos below her list of links. Iy’s supposed to have sound, and it definitely has CC.

April, in the South, is Confederate Heritage Month. The Southrern Poverty Law Center find that less than acceptable. So they are pushing for a celebreation of good things in southern history to replace it – or at least alleviate the bad taste of it.

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Apr 062024
 

When I saw this article (and particularly when I learned something else I’ll get to after the article). I figured I had to go right to the top – Athena, the goddess of wisdom. Athena is likely so intellectual because she wasn’t born as we understand it – she emerged fully formed and an adult from Zeus’s head (I assume without the helmet, although the size of the helmet does suggest a large brain.)

At a time when we are aware that Alzheimer’s disease exists, and that there is no cure, many of us are terrified of it – of having it ourselves, and of it happening to someone near and dear. I know my mother was terrified of it. (She was spared it – she was still expertly solving crossword puzzles until her final coma, caused by pneumonia, at age 93.) So I can’t imagine anyone willing to miss out on any opportunity to avoid it, or to slow its progress.
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New studies suggest millions with mild cognitive impairment go undiagnosed, often until it’s too late

Mild cognitive impairment can be an early sign of Alzheimer’s disease or other dementias.
ivanastar/iStock via Getty Images Plus

Soeren Mattke, University of Southern California and Ying Liu, USC Dornsife College of Letters, Arts and Sciences

Mild cognitive impairment – an early stage of dementia – is widely underdiagnosed in people 65 and older. That is the key takeaway of two recent studies from our team.

In the first study, we used Medicare data for about 40 million beneficiaries age 65 and older from 2015 to 2019 to estimate the prevalence of mild cognitive impairment in that population and to identify what proportion of them had actually been diagnosed.

Our finding was sobering: A mere 8% of the number of cases with mild cognitive impairment that we expected based on a statistical model had actually been diagnosed. Scaled up to the general population 65 and older, this means that approximately 7.4 million cases across the country remain undiagnosed.

In the second study, we analyzed data for 226,756 primary care clinicians and found that over 99% of them underdiagnosed mild cognitive impairment in this population.

Why it matters

Mild cognitive impairment is an early symptom of Alzheimer’s disease in about half of cases and progresses to dementia at a rate of 10% to 15% per year. It includes symptoms such as losing the ability to remember recent events and appointments, make sound decisions and master complex tasks. Failure to detect it might deprive patients of an opportunity to get treated and to slow down disease progression.

Mild cognitive impairment can sometimes be caused by easily addressable factors, such as medication side effects, thyroid dysfunction or vitamin B12 deficiency. Since mild cognitive impairment has the same risk factors as cardiovascular disease, such as high blood pressure and cholesterol, medication management of these risks combined with diet and exercise can reduce the risk of progression.

In 2023, the Food and Drug Administration approved the drug lecanemab as the first disease-modifying treatment for Alzheimer’s disease, the most common cause of mild cognitive impairment. In contrast to previous drugs, which can temporarily improve symptoms of the disease, such as memory loss and agitation, this new treatment addresses the underlying cause of the disease.

Lecanemab, a monoclonal antibody, reduces amyloid plaques in the brain, which are toxic protein clumps that are believed to contribute to the progression of the disease. In a large clinical trial, lecanemab was able to reduce the progression of early-stage Alzheimer’s disease. A similar drug, donanemab, also succeeded in a clinical trial and is expected to be approved sometime in 2024.

However, these drugs must be used in the early stages of Alzheimer’s disease, ideally when a patient has only mild cognitive impairment, as there is no evidence that they are effective in advanced stages.

An earlier diagnosis leads to early treatment and better outcomes.

What still isn’t known

Many factors contribute to the lack of timely detection. But researchers don’t have a good understanding of the relative importance of those individual factors or how to reduce the high rate of underdiagnosis.

While distinct, symptoms are subtle and their slow progression means that they can be overlooked or misinterpreted as normal aging. A neurologist in China told our research team that diagnosis rates spike in China after the New Year’s holiday, when children who haven’t seen their parents for a year notice changes that are harder to pick up when interacting with someone daily.

Doctors also commonly discount memory concerns as normal aging and doubt that much can be done about it. While cognitive tests to distinguish mild cognitive impairment from pathologic decline do exist, they take about 15 minutes, which can be hard to come by during the limited time of a doctor’s visit and may require a follow-up appointment.

What’s next

People, particularly those in their 60s and beyond, as well as their families and friends need to be vigilant about cognitive decline, bring it up during doctor’s appointments and insist on a formal assessment.

The Medicare yearly “wellness” visit is an opportunity to explore such concerns, but only about half of beneficiaries take advantage of it.

Just as physicians ask patients about unexplained weight loss and take those concerns seriously, we believe questions that explore a patient’s cognitive state need to become the norm.

The Research Brief is a short take on interesting academic work.The Conversation

Soeren Mattke, Director of the USC Dornsife Brain Health Observatory, University of Southern California and Ying Liu, Research Scientist, Center for Economic and Social Research, USC Dornsife College of Letters, Arts and Sciences

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Pat B, (who is celebrating her fiftieth wedding anniversary today) has graciously given me permission to share that this coming Friday she has an appointment with her Doctor to discuss her memory loss. While no one can prove it, I would not be surprised to learn this was inspired by Athena. I can’t imagine anything wiser than getting checked out for any possible signs of dementia, knowing that waiting will not make it any better but it could make it worse. Thank you, Athena, and may you inspire all of us who are 65 or older to be wise also.

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